诺拉·奥唐奈:我从医生那里学到的关于更年期的知识


2026年8月12日 美国东部时间07:00:29 / 哥伦比亚广播公司新闻

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在本周的《健康生活》专栏中,我与我的私人医生雷切尔·鲁宾坐下来探讨了更年期这个重要话题:你的身体会发生哪些变化,为何女性可能在毫无必要地承受痛苦,以及你实际上可以采取哪些应对措施。

以下是我们对话中我学到的内容,视频现已在YouTube上线,你也可以在任意播客平台收听:

更年期被称为“一种去势事件”

“无论我们是否愿意接受,无论更年期是自然发生还是其他情况,它本质上就是一种去势事件,”鲁宾医生说道。“无论它是否本该发生,我们的寿命都已经超过了卵巢的存续期限。”

鲁宾将更年期描述为卵巢功能完全停止:你的卵巢不再分泌雌激素、孕酮或睾酮。“你不再分泌生育年龄阶段的那些激素,而这会产生一系列后果,因为你的全身都分布着激素受体,”她解释道。

每个人的症状严重程度和表现各不相同,但女性通常会出现潮热、睡眠障碍、情绪波动、体重增加和记忆力减退等问题。

虽然鲁宾表示,男性随着年龄增长也会出现睾酮水平自然下降的情况,但他们“并不会真正降到‘去势’后的水平”。她用油箱类比来解释自己的去势说法:“女性的油箱已经空了。而男性的油箱大概还保持在半箱油的状态,如果降到四分之一箱,他们可以去看医生,开一些睾酮,就能回到半箱到四分之三箱的状态,感觉会好很多。”

阴道激素可以预防尿路感染——并为联邦医疗保险节省数十亿美元

尿路感染在更年期期间和绝经后都很常见,如果不及时治疗,可能会引发败血症、住院甚至死亡。正因如此,鲁宾表示,她认为所有更年期女性都应该使用阴道激素,这种激素可以改善尿道微生物群,从而预防尿路感染。

目前,尽管美国泌尿学会支持使用阴道雌激素,且该疗法通常在保险覆盖范围内,但只有不到十分之一的绝经后女性在使用阴道雌激素。

鲁宾援引急诊就诊、住院和重症监护病房收治的相关成本表示,为女性提供阴道雌激素每年可以为联邦医疗保险节省60亿至220亿美元。

女性实际产生的睾酮比雌激素更多

你需要依靠睾酮在卵巢中合成雌激素——而女性产生的睾酮量其实多于雌激素。

鲁宾表示,全球医学界已达成共识,睾酮可以帮助更年期和围绝经期女性改善性欲低下的问题,但目前尚无美国食品药品监督管理局批准的女性专用睾酮产品。不过,该药物可以超适应症处方。鲁宾说,她的服用睾酮的患者告诉她,这种药物带来的好处不止改善性欲——患者复诊时会说:“我终于感觉更像我自己了。”

我之前从未公开谈论过这件事,但我确实在使用鲁宾医生开的睾酮——它装在通常给男性开具的药膏管中,但我使用的剂量要小得多。我并没有突然意识到它的效果,但随着时间推移,结合其他激素治疗,我逐渐感受到了它的作用。

Norah O’Donnell: What I learned from my doctor about menopause

2026-08-12 07:00:29 EDT / CBS News

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For this week’s “Healthful,” I sat down with my very own doctor, Rachel Rubin, to tackle the important topic of menopause: How your body changes, why women may be needlessly suffering, and what you can actually do about it.

Here’s what I learned in our conversation, streaming now on YouTube and available wherever you listen to your podcasts:

Menopause as “a castration event”

“Menopause is a castration event, whether we like it or not, whether it’s natural or not,” Dr. Rubin said. “Whether it’s supposed to happen or not, we are outliving our ovaries.”

Rubin described menopause as essentially the ovarian function turning off: Your ovaries no longer make estrogen, progesterone or testosterone. “You’re not making the hormones that you were during your reproductive years, and that has consequences because you have hormone receptors throughout your entire body,” she explained.

The severity and symptoms are different for everyone, but women commonly experience hot flashes, poor sleep, mood changes, weight gain and memory issues.

While Rubin said some men see a natural decline of testosterone as they age, they “don’t really get to ‘castrate’ levels.” She explained her castration remarks in the context of a gas tank analogy: “Women, their gas tank is zero. Men, they kind of live at like half a tank, and maybe if they get to a quarter of the tank, they can go to their doctor, they get some testosterone, and they go back to half to three-quarters tank and they feel great.”

Vaginal hormones can prevent UTIs — and save billions in Medicare

Urinary tract infections are common during and after menopause, and if untreated, can lead to sepsis, hospitalization and even death. It’s why Rubin said she thinks all menopausal women should be offered vaginal hormones, which fix the urinary tract’s microbiome and can prevent UTIs.

Right now, fewer than one in 10 postmenopausal women are using vaginal estrogen, even though its use is supported by the American Urological Association, and it’s often covered by insurance.

Rubin said giving women vaginal estrogen could save Medicare $6 billion to $22 billion a year, citing costs around urgent care visits, hospitalizations and ICU admissions.

Women actually produce more testosterone than estrogen

You need testosterone to make estrogen in the ovaries — and women make more testosterone than estrogen.

Rubin said there’s global consensus that testosterone helps menopausal and perimenopausal women with low libido, but there’s no FDA-approved testosterone product for women. Although, it can be prescribed off-label. Rubin said her patients who take testosterone tell her it helps with more than libido — that patients come back and say, “I just feel more like me.”

I’ve never talked about this publicly before, but I use testosterone prescribed by Rubin — it comes in a tube that’s normally prescribed to men, but I administer it in much smaller doses. There wasn’t an “aha” moment for me, but I noticed its effects over time, and in concert with other hormones.

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